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Literature summary for 1.2.1.11 extracted from

  • Cahyanto, M.N.; Kawasaki, H.; Nagashio, M.; Fujiyama, K.; Seki, T.
    Construction of Lactobacillus plantarum strain with enhanced L-lysine yield (2007), J. Appl. Microbiol., 102, 674-679.
    View publication on PubMed
Search for more literature for 1.2.1.11

Cloned(Commentary)

Cloned (Comment) Organism
co-expression with L-lysine-insensitive aspartokinase, dihydrodipicolinate synthase, and dihydrodipicolinate reductase in the parent strain and in an AEC-resistant mutant strain of Lactobacillus plantarum from a shuttle vector, leading to increased L-lysine production, but absolutely requiring overexpression of aspartokinase or dihydrodipicolinate synthase, overview Lactiplantibacillus plantarum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-aspartate 4-semialdehyde + phosphate + NADP+ Lactiplantibacillus plantarum
-
 L-4-aspartyl phosphate + NADPH + H+
-
 ?
L-aspartate 4-semialdehyde + phosphate + NADP+ Lactiplantibacillus plantarum IAM 12477
-
 L-4-aspartyl phosphate + NADPH + H+
-
 ?

Organism

Organism UniProt Comment Textmining
Lactiplantibacillus plantarum
-
-
-
Lactiplantibacillus plantarum IAM 12477
-
-
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 lysine production activity in recombinant strains, overview Lactiplantibacillus plantarum

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-aspartate 4-semialdehyde + phosphate + NADP+
-
 Lactiplantibacillus plantarum L-4-aspartyl phosphate + NADPH + H+
-
 ?
L-aspartate 4-semialdehyde + phosphate + NADP+
-
 Lactiplantibacillus plantarum IAM 12477 L-4-aspartyl phosphate + NADPH + H+
-
 ?

Synonyms

Synonyms Comment Organism
aspartate semialdehyde dehydrogenase
-
 Lactiplantibacillus plantarum

Cofactor

Cofactor Comment Organism Structure
NADP+
-
 Lactiplantibacillus plantarum