Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.2.1.105 extracted from

  • Araujo, W.L.; Nunes-Nesi, A.; Trenkamp, S.; Bunik, V.I.; Fernie, A.R.
    Inhibition of 2-oxoglutarate dehydrogenase in potato tuber suggests the enzyme is limiting for respiration and confirms its importance in nitrogen assimilation, (2008), Plant Physiol., 148, 1782-1796.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.2.1.105

Inhibitors

Inhibitors Comment Organism Structure
succinyl phosphonate potent, slow-binding inhibitor of the 2-oxoglutarate dehydrogenase complex, complete inhibition at 0.1 mM Solanum tuberosum
succinyl phosphonate carboxy ethyl ester potent, slow-binding inhibitor of the 2-oxoglutarate dehydrogenase complex, complete inhibition at 0.1 mM Solanum tuberosum
succinyl phosphonate diethyl ester poor inhibitor of the 2-oxoglutarate dehydrogenase complex Solanum tuberosum
succinyl phosphonate phosphono ethyl ester poor inhibitor of the 2-oxoglutarate dehydrogenase complex Solanum tuberosum
succinyl phosphonate triethyl ester
-
 Solanum tuberosum

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Solanum tuberosum 5739
-

Organism

Organism UniProt Comment Textmining
Solanum tuberosum
-
 cultivar Desiree
-

Source Tissue

Source Tissue Comment Organism Textmining
tuber
-
 Solanum tuberosum
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-oxoglutarate + [dihydrolipoyllysine-residue succinyltransferase] lipoyllysine
-
 Solanum tuberosum [dihydrolipoyllysine-residue succinyltransferase] S-succinyldihydrolipoyllysine + CO2
-
 ?

Synonyms

Synonyms Comment Organism
2-oxoglutarate dehydrogenase complex tricarboxylic acid cycle multienzyme Solanum tuberosum

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Solanum tuberosum
thiamine diphosphate
-
 Solanum tuberosum