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Literature summary for 1.2.1.105 extracted from

  • Bunik, V.I.; Degtyarev, D.
    Structure-function relationships in the 2-oxo acid dehydrogenase family: substrate-specific signatures and functional predictions for the 2-oxoglutarate dehydrogenase-like proteins (2008), Proteins, 71, 874-890.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
Geobacillus stearothermophilus 5739
-
mitochondrion
-
Homo sapiens 5739
-

Organism

Organism UniProt Comment Textmining
Geobacillus stearothermophilus
-
-
-
Homo sapiens Q96HY7
-
-
Homo sapiens Q9ULD0
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-oxoglutarate + [dihydrolipoyllysine-residue succinyltransferase] lipoyllysine
-
Geobacillus stearothermophilus [dihydrolipoyllysine-residue succinyltransferase] S-succinyldihydrolipoyllysine + CO2
-
?
2-oxoglutarate + [dihydrolipoyllysine-residue succinyltransferase] lipoyllysine
-
Homo sapiens [dihydrolipoyllysine-residue succinyltransferase] S-succinyldihydrolipoyllysine + CO2
-
?

Synonyms

Synonyms Comment Organism
2-oxoglutarate dehydrogenase
-
Geobacillus stearothermophilus
2-oxoglutarate dehydrogenase
-
Homo sapiens
DHTKD1 2-oxoglutarate dehydrogenase-like hypothetical protein Homo sapiens
E1o
-
Geobacillus stearothermophilus
OGDHL 2-oxoglutarate dehydrogenase-like hypothetical protein Homo sapiens

Cofactor

Cofactor Comment Organism Structure
thiamine diphosphate
-
Geobacillus stearothermophilus
thiamine diphosphate
-
Homo sapiens