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Literature summary for 1.2.1.104 extracted from

  • Held, N.M.; Kuipers, E.N.; van Weeghel, M.; van Klinken, J.B.; Denis, S.W.; Lombes, M.; Wanders, R.J.; Vaz, F.M.; Rensen, P.C.N.; Verhoeven, A.J.; Boon, M.R.; Houtkooper, R.H.
    Pyruvate dehydrogenase complex plays a central role in brown adipocyte energy expenditure and fuel utilization during short-term beta-adrenergic activation (2018), Sci. Rep., 8, 9562 .
    View publication on PubMedView publication on EuropePMC
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Organism

Organism UniProt Comment Textmining
Mus musculus
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Source Tissue

Source Tissue Comment Organism Textmining
adipocyte
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 Mus musculus
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T-37i cell
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 Mus musculus
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General Information

General Information Comment Organism
physiological function in T37i murine preadipocytes differentiated into brown adipocytes, the flux through the TCA cycle is enhanced and regulated by pyruvate dehydrogenase (PDH) activity. PDH plays an important role in directing glucose carbons towards oxidation Mus musculus