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Literature summary for 1.2.1.104 extracted from

  • Song, L.; Liu, D.
    Mutations in the three Arabidopsis genes that encode the E2 subunit of the mitochondrial pyruvate dehydrogenase complex differentially affect enzymatic activity and plant growth (2015), Plant Cell Rep., 34, 1919-1926 .
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
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Arabidopsis thaliana 5739
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Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana Q0WQF7 and Q8RWN9 Q0WQF7 i.e. dihydrolipoyllysine-residue acetyltransferase subunit 1 of pyruvate dehydrogenase complex, Q8RWN9 i.e. subunit 2 and Q5M729, i.e subunit 3, respectively, cf. EC 2.3.1.12
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Synonyms

Synonyms Comment Organism
At1g54220 gene name, component 3 Arabidopsis thaliana
At3g13930 gene name, component 2 Arabidopsis thaliana
At3g52200 gene name, component 1 Arabidopsis thaliana
Lta3
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Arabidopsis thaliana

General Information

General Information Comment Organism
physiological function knockdown of the expression of the subunit 1 of the E2 dihydrolipoyllysine-residue acetyltransferase gene to 17 % of that in the wild-type has only a slight effect on plant growth whereas knockout of subunit 2 leads to an embryo-lethal phenotype. The nearly null mutation of subunit 3 does not cause any developmental abnormality Arabidopsis thaliana