Literature summary for 1.2.1.104 extracted from

Severin, S.E.; Khailova, L.S.; Gomazkova, V.S.
Dehydrogenases of alpha-keto acids: essential groups of the active centers (1986), Adv. Enzyme Regul., 25, 347-375.

Search for more literature for 1.2.1.104

Inhibitors

Inhibitors	Comment	Organism	Structure
2,3-Butanedione	10 mM, biphasic kinetic, complete inactivation after 20 min	Pigeon
5,5'-dithiobis(2-nitrobenzoate)	-	Pigeon
diethyldicarbonate	-	Pigeon
p-chloromercuribenzoate	0.026 mM, complete inactivation after 80 s	Pigeon
Phenylglyoxal	10 mM, biphasic kinetic, complete inactivation after 30 min	Pigeon

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
37000	-	alpha2,beta2, 2 * 42000 + 2 * 37000, SDS-PAGE	Pigeon
42000	-	alpha2,beta2, 2 * 42000 + 2 * 37000, SDS-PAGE	Pigeon

Organism

Organism	UniProt	Comment	Textmining
Pigeon	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
pectoral muscle	-	Pigeon	-

Subunits

Subunits	Comment	Organism
tetramer	alpha2,beta2, 2 * 42000 + 2 * 37000, SDS-PAGE	Pigeon

Cofactor

Cofactor	Comment	Organism	Structure
thiamine diphosphate	two binding sites	Pigeon

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Release 2023.1 (January 2023)