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Literature summary for 1.17.99.2 extracted from

  • Szaleniec, M.; Borowski, T.; Schuehle, K.; Witko, M.; Heider, J.
    Ab initio modeling of ethylbenzene dehydrogenase reaction mechanism (2010), J. Am. Chem. Soc., 132, 6014-6024.
    View publication on PubMed

Metals/Ions

Metals/Ions Comment Organism Structure
Molybdenum molybdopterin enzyme Aromatoleum aromaticum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Aromatoleum aromaticum EBDH is a bacterial molybdopterin enzyme capable of stereospecific anaerobic hydroxylation of alkylaromatic compounds to secondary alcohols ?
-
?
ethylbenzene + H2O + acceptor Aromatoleum aromaticum
-
(S)-1-phenylethanol + reduced acceptor
-
?

Organism

Organism UniProt Comment Textmining
Aromatoleum aromaticum
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information EBDH is a bacterial molybdopterin enzyme capable of stereospecific anaerobic hydroxylation of alkylaromatic compounds to secondary alcohols Aromatoleum aromaticum ?
-
?
ethylbenzene + H2O + acceptor
-
Aromatoleum aromaticum (S)-1-phenylethanol + reduced acceptor
-
?

Synonyms

Synonyms Comment Organism
ethylbenzene dehydrogenase
-
Aromatoleum aromaticum
EBDH
-
Aromatoleum aromaticum

pH Range

pH Minimum pH Maximum Comment Organism
4.5 9
-
Aromatoleum aromaticum

Cofactor

Cofactor Comment Organism Structure
molybdenum cofactor
-
Aromatoleum aromaticum

General Information

General Information Comment Organism
physiological function EBDH is a bacterial molybdopterin enzyme capable of stereospecific anaerobic hydroxylation of alkylaromatic compounds to secondary alcohols. It is a key biocatalyst in the metabolism of ethylbenzene-degrading bacteria such as Aromatoleum aromaticum, which converts ethylbenzene to (S)-1-phenylethanol Aromatoleum aromaticum