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Literature summary for 1.17.4.4 extracted from

  • Caspers, M.; Czogalla, K.J.; Liphardt, K.; Mueller, J.; Westhofen, P.; Watzka, M.; Oldenburg, J.
    Two enzymes catalyze vitamin K 2,3-epoxide reductase activity in mouse VKORC1 is highly expressed in exocrine tissues while VKORC1L1 is highly expressed in brain (2015), Thromb. Res., 135, 977-983 .
    View publication on PubMed
Search for more literature for 1.17.4.4

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Mus musculus
-
-

Organism

Organism UniProt Comment Textmining
Mus musculus Q6TEK5
-
-
Mus musculus Q9CRC0
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain highly expressed Mus musculus
-
liver
-
 Mus musculus
-
lung
-
 Mus musculus
-
mammary gland
-
 Mus musculus
-
prostate
-
 Mus musculus
-
salivary gland
-
 Mus musculus
-

Synonyms

Synonyms Comment Organism
VKORC1
-
 Mus musculus
VKORC1L1
-
 Mus musculus

General Information

General Information Comment Organism
metabolism VKORC1 is the key enzyme of the classical vitamin K cycle by which vitamin K-dependent proteins are gamma-carboxylated by the hepatic gamma-glutamyl carboxylase Mus musculus
metabolism VKORC1L1 is chiefly responsible for antioxidative function by reduction of vitamin K to prevent damage by intracellular reactive oxygen species Mus musculus