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Literature summary for 1.17.4.4 extracted from

  • Fernandez, I.; Vijayakumar, P.; Marques, C.; Cancela, M.L.; Gavaia, P.J.; Laize, V.
    Zebrafish vitamin K epoxide reductases expression in vivo, along extracellular matrix mineralization and under phylloquinone and warfarin in vitro exposure (2015), Fish Physiol. Biochem., 41, 745-759 .
    View publication on PubMed
Search for more literature for 1.17.4.4

Inhibitors

Inhibitors Comment Organism Structure
warfarin
-
 Danio rerio

Organism

Organism UniProt Comment Textmining
Danio rerio E7F6X2 vitamin K epoxide reductase complex subunit 1 (Vkorc1)
-
Danio rerio Q502B2 vitamin K epoxide reductase complex subunit 1-like 1 (Vkorc1l1)
-

Source Tissue

Source Tissue Comment Organism Textmining
brain highest expression in muscle and brain Danio rerio
-
eye intermediate expression level Danio rerio
-
eye intermediate level of expresssion Danio rerio
-
gill low expression level Danio rerio
-
liver intermediate expression level Danio rerio
-
muscle highest expression in muscle and brain Danio rerio
-
ovary highly expressed Danio rerio
-
skin low expression level Danio rerio
-
spleen intermediate level of expresssion Danio rerio
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stomach low level of expression Danio rerio
-
vertebra intermediate expression level Danio rerio
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vertebra intermediate level of expresssion Danio rerio
-

Expression

Organism Comment Expression
Danio rerio level of vkorc1l1 expression is the highest at 4-cell stage, diminishing at Prim-5 stage and remaining stable afterward down
Danio rerio level of vkorc1l1 expression is the highest at 4-cell stage, diminishing at Prim-5 stage and remaining stable afterward. Significantly overexpressed in differentiating cells (T1M) but not in mineralizating (T3M) cells up
Danio rerio Vkorc1 is detected at 4-cell stage but shows an expression peak at 72-96 h post fertilization, and a lower and stable gene expression value afterward. Significantly overexpressed in differentiating (T1M) but not in mineralizating (T3M) cells up