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Literature summary for 1.17.4.4 extracted from
- VKORC1 and the vitamin K cycle (2008), Vitam. Horm., 78, 23-33.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Sf9 insect cells | Homo sapiens |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| (R)-warfarin | - |
Homo sapiens |  |
| (S)-warfarin | - |
Homo sapiens | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| endoplasmic reticulum | - |
Homo sapiens | 5783 | - |
| membrane | transmembrane protein | Homo sapiens | 16020 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 18000 | - |
- |
Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| vitamin K 2,3-epoxide + oxidized dithiothreitol | - |
Homo sapiens | vitamin K + 1,4-dithiothreitol | - |
ir | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| vitamin K epoxide reductase complex subunit 1 | - |
Homo sapiens |
| VKORC1 | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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