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Literature summary for 1.17.4.4 extracted from
- Consequences of the Y139F Vkorc1 mutation on resistance to AVKs: in-vivo investigation in a 7th generation of congenic Y139F strain of rats (2009), Pharmacogenet. Genomics, 19, 742-750.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| Y139F | the mutation mediates resistance towards chlorophacinone and bromadiolone | Rattus norvegicus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| bromadiolone | - |
Rattus norvegicus |  |
| chlorophacinone | - |
Rattus norvegicus | |
| Difenacoum | - |
Rattus norvegicus | |
| difethialone | - |
Rattus norvegicus | |
| warfarin | - |
Rattus norvegicus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
| Rattus norvegicus Y139F | - |
- |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| vitamin K-2,3-epoxide reductase subunit 1 | - |
Rattus norvegicus |
| VKORC1 | - |
Rattus norvegicus |
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