Cloned (Comment) | Organism |
---|---|
two-hybrid interaction analysis of CSN7 and RNR2 expressing the vectors under control of the 35S promoter in Nicotiana benthamiana cells, transgenic expression of RNR2 in Arabidopsis thaliana plants | Arabidopsis thaliana |
Protein Variants | Comment | Organism |
---|---|---|
additional information | construction of two T-DNA insertion mutants of the RNR2Tso2, inserted within the coding sequence of the second exon of RNR2Tso2. No plants homozygous for the T-DNA allele are detectable for either allele | Arabidopsis thaliana |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
signalosome protein complex COP9 | i.e. CSN, is a negative regulator of RNR2 activity in Arabidopsis thaliana. The pleiotropic regulator of plant development and contains eight-subunits, RNR2 binds to the C-terminus of subunit 7, CSN7; i.e. CSN, is a negative regulator of RNR2 activity in Arabidopsis thaliana. The pleiotropic regulator of plant development and contains eight-subunits, RNR2 binds to the C-terminus of subunit 7, CSN7 | Arabidopsis thaliana |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | the subcellular localization of RNR2 is primarily nuclear in meristematic regions, and cytoplasmic in adult cells. RNR2 is constitutively nuclear in csn7 mutant seedlings | Arabidopsis thaliana | 5737 | - |
nucleus | the subcellular localization of RNR2 is primarily nuclear in meristematic regions, and cytoplasmic in adult cells. RNR2 is constitutively nuclear in csn7 mutant seedlings | Arabidopsis thaliana | 5634 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Arabidopsis thaliana | the small subunit of RNR2 interacts in planta with the C-terminal section of signalosome protein complex COP9 subunit 7, CSN7, overview | ? | - |
? | |
additional information | Arabidopsis thaliana Col-0 | the small subunit of RNR2 interacts in planta with the C-terminal section of signalosome protein complex COP9 subunit 7, CSN7, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Arabidopsis thaliana | P50651 | small subunit C of RNR, RNR2a | - |
Arabidopsis thaliana | Q9LSD0 | small subunit C of RNR, RNR2tso | - |
Arabidopsis thaliana Col-0 | P50651 | small subunit C of RNR, RNR2a | - |
Arabidopsis thaliana Col-0 | Q9LSD0 | small subunit C of RNR, RNR2tso | - |
Purification (Comment) | Organism |
---|---|
recombinant RNR2 from transgenic Arabidopsis thaliana plants by affinity chromatography | Arabidopsis thaliana |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
meristem | - |
Arabidopsis thaliana | - |
additional information | RNR2Tso2 is more prevalent than RNR2A throughout development and in most organs, suggesting that RNR2Tso2 is the predominant RNR2 in Arabidopsis thaliana. RNR2Tso2 levels are more varied than RNR2A levels in response to environmental changes and exposure to chemicals | Arabidopsis thaliana | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the small subunit of RNR2 interacts in planta with the C-terminal section of signalosome protein complex COP9 subunit 7, CSN7, overview | Arabidopsis thaliana | ? | - |
? | |
additional information | the small subunit of RNR2 interacts in planta with the C-terminal section of signalosome protein complex COP9 subunit 7, CSN7, overview | Arabidopsis thaliana Col-0 | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ribonucleotide reductase | - |
Arabidopsis thaliana |
RNR2 | small subunit of RNR | Arabidopsis thaliana |
General Information | Comment | Organism |
---|---|---|
additional information | RNR2Tso2 is essential in Col-0 | Arabidopsis thaliana |