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Literature summary for 1.17.4.2 extracted from

  • Camier, S.; Ma, E.; Leroy, C.; Pruvost, A.; Toledano, M.; Marsolier-Kergoat, M.C.
    Visualization of ribonucleotide reductase catalytic oxidation establishes thioredoxins as its major reductants in yeast (2007), Free Radic. Biol. Med., 42, 1008-1016.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
additional information cell lacking thioredoxins exhibit an elongated S phase and accumulate subunit R1 in its oxidized form. Cells also contain significantly decreased deoxyribonucleotide levels during the S phase. Overexpressing subunit R1 in these cells increases both the amount of R1 reduced form and the concentrations of deoxyribonucleotides and accelerates DNA replication Saccharomyces cerevisiae

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
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