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Literature summary for 1.17.4.1 extracted from

  • Zhu, M.; Dai, X.; Guo, W.; Ge, Z.; Yang, M.; Wang, H.; Wang, Y.P.
    Manipulating the bacterial cell cycle and cell size by titrating the expression of ribonucleotide reductase (2017), mBio, 8, e01741-17 .
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
molecular biology titration of ribonucleotide reductase expression can serve as a standard model system for studying the coordination between chromosome replication, cell division, and cell size Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli P00452 and P69924 P00452: subunit alpha (NrdA), P69924: subunit beta (NrdB)
-

Synonyms

Synonyms Comment Organism
class Ia RNR
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Escherichia coli

Expression

Organism Comment Expression
Escherichia coli ribonucleotide reductase overexpression leads to a shortened chromosome replication (C period) compared with that of a wild-type strain up

General Information

General Information Comment Organism
metabolism the reduction of ribonucleoside diphosphate to deoxyribonucleoside diphosphate is the rate-limiting step in dNTP production Escherichia coli