Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | enzyme from Novikoff hepatoma tumor cells is associated with a smooth membrane component of the cytoplasm | Rattus norvegicus | 5737 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ribonucleoside diphosphate + reduced thioredoxin | Rattus norvegicus | critical and rate-controlling step in pathway leading to DNA synthesis and cell replication | 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O | - |
? | |
ribonucleoside diphosphate + reduced thioredoxin | Rattus norvegicus | thioredoxin is the physiological reductant | 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
Morris hepatoma cells | - |
Rattus norvegicus | - |
Novikoff hepatoma cells | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
strong increase of specific activity during growth of Novikoff hepatoma cells | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ribonucleoside diphosphate + reduced thioredoxin | - |
Rattus norvegicus | 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O | - |
ir | |
ribonucleoside diphosphate + reduced thioredoxin | critical and rate-controlling step in pathway leading to DNA synthesis and cell replication | Rattus norvegicus | 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O | - |
? | |
ribonucleoside diphosphate + reduced thioredoxin | thioredoxin is the physiological reductant | Rattus norvegicus | 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O | - |
? |