Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | L1210 cells with resistance to specific nucleotide reductase inhibitors | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
wild-type and reductase inhibitor resistant L1210 cell line | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
L-1210 cell | L1210 cells resistant to specific ribonucleotide reductase inhibitors | Mus musculus | - |
L-cell | cell line | Mus musculus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
extracts from hydroxyurea resistant cell line HU-7 exhibit a 13fold higher ADP reductase activity and a 5fold higher CDP reductase activity when compared to wild-type | Mus musculus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ribonucleoside diphosphate + reduced thioredoxin | - |
Mus musculus | 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O | - |
ir |