Inhibitors | Comment | Organism | Structure |
---|---|---|---|
allopurinol | - |
Mus musculus | |
ioniceraflavone | i.e. 5,5'',7,7''-tetrahydroxy-2,2''-di(p-hydroxyphenyl)-2'',3''-dihydro[3,6'']bichromenyl-4,4''-dione, from ethanolic leaf extracts of Lonicera hypoglauca | Mus musculus | |
additional information | ethanol leaf extracts of Lonicera hypoglauca, an endemic rattan growing in Taiwan, inhibits xanthine oxidase and reduces serum uric acid in mice, overview | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
xanthine + O2 + H2O | Mus musculus | - |
urate + H2O2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
xanthine + O2 + H2O | - |
Mus musculus | urate + H2O2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
XOD | - |
Mus musculus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
assay at | Mus musculus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
additional information | - |
IC50 of licewraflavone is 0.00085 mg/ml and for allopurinol is 0.00040 mg/ml | Mus musculus | additional information |
General Information | Comment | Organism |
---|---|---|
malfunction | the enzyme is a key enzyme in th epathogenesis of hyperuricemia | Mus musculus |