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Literature summary for 1.17.1.4 extracted from

  • Zhao, X.; Zhu, J.X.; Mo, S.F.; Pan, Y.; Kong, L.D.
    Effects of cassia oil on serum and hepatic uric acid levels in oxonate-induced mice and xanthine dehydrogenase and xanthine oxidase activities in mouse liver (2006), J. Ethnopharmacol., 103, 357-365.
    View publication on PubMed

Application

Application Comment Organism
medicine oral adminstration of cassia oil significantly reduces serum and hepatic urate levels in hyperuricemic mice. At 600mg/kg, cassia oil is as potent as allopurinol. This hypouricemic effect is explained by inhibiting activities of liver xanthine oxidase and xanthine oxidoreductase Mus musculus

Inhibitors

Inhibitors Comment Organism Structure
cassia oil oral adminstration of cassia oil significantly reduces serum and hepatic urate levels in hyperuricemic mice. At 600 mg/kg, cassia oil is as potent as allopurinol. This hypouricemic effect is explained by inhibiting activities of liver xanthine oxidase and xanthine oxidoreductase Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
hyperuricemic mice induced by potassium oxonate
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Mus musculus
-