BRENDA - Enzyme Database show
show all sequences of 1.17.1.3

Proanthocyanidin synthesis in Theobroma cacao: genes encoding anthocyanidin synthase, anthocyanidin reductase, and leucoanthocyanidin reductase

Liu, Y.; Shi, Z.; Maximova, S.; Payne, M.J.; Guiltinan, M.J.; BMC Plant Biol. 13, 202 (2013)

Data extracted from this reference:

Cloned(Commentary)
Commentary
Organism
recombinantly expressed in Escherichia coli
Theobroma cacao
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Theobroma cacao
-
-
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
flower
-
Theobroma cacao
-
leaf
-
Theobroma cacao
-
pod
pod exocarp
Theobroma cacao
-
seed
-
Theobroma cacao
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3,4-cis-leucoanthocyanidin + NADPH
-
727256
Theobroma cacao
2,3-trans-catechin + NADP+ + H2O
-
-
-
?
Temperature Optimum [°C]
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
30
-
assay at
Theobroma cacao
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
7
-
assay at
Theobroma cacao
Cloned(Commentary) (protein specific)
Commentary
Organism
recombinantly expressed in Escherichia coli
Theobroma cacao
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
flower
-
Theobroma cacao
-
leaf
-
Theobroma cacao
-
pod
pod exocarp
Theobroma cacao
-
seed
-
Theobroma cacao
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3,4-cis-leucoanthocyanidin + NADPH
-
727256
Theobroma cacao
2,3-trans-catechin + NADP+ + H2O
-
-
-
?
Temperature Optimum [°C] (protein specific)
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
30
-
assay at
Theobroma cacao
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
7
-
assay at
Theobroma cacao
General Information
General Information
Commentary
Organism
malfunction
transgenic tobacco overexpressing TcLAR have decreased amounts of anthocyanidins and increased proanthocyanidins. Overexpressing TcLAR in Arabidopsis ldox mutant also results in elevated synthesis of not only catechin but also epicatechin
Theobroma cacao
General Information (protein specific)
General Information
Commentary
Organism
malfunction
transgenic tobacco overexpressing TcLAR have decreased amounts of anthocyanidins and increased proanthocyanidins. Overexpressing TcLAR in Arabidopsis ldox mutant also results in elevated synthesis of not only catechin but also epicatechin
Theobroma cacao
Other publictions for EC 1.17.1.3
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
746163
Wang
Evolutionary and functional c ...
Camellia sinensis
Planta
247
139-154
2018
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9
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743899
Kumar
Pyramiding of tea dihydroflav ...
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3 Biotech
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2017
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Metabolic characterization of ...
Camellia sinensis
Molecules
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2017
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Liu
A role for leucoanthocyanidin ...
Medicago truncatula, Medicago truncatula ecotype R108
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2016
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Different alleles of a gene e ...
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2016
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Accumulation of flavanols and ...
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2015
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Transcriptome and biochemical ...
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PLoS ONE
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Transcripts of anthocyanidin ...
Fagopyrum tataricum
ScientificWorldJournal
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1
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1
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9
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1
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726337
Wang
Isolation and characterization ...
Populus trichocarpa
PLoS ONE
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Liu
Proanthocyanidin synthesis in ...
Theobroma cacao
BMC Plant Biol.
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2013
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1
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4
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Mewan, K.M.; Sumner, L.W.; Yu ...
Camellia sinensis
Plant Physiol.
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2013
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Molecular cloning and characte ...
Populus trichocarpa
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2012
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2010
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Involvement of abscisic acid i ...
Vitis vinifera
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1
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2
2
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700789
Gagne
Leucoanthocyanidin reductase a ...
Vitis vinifera
Plant Physiol. Biochem.
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2009
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2
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6
1
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1
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676629
Paolocci
Ectopic expression of a basic ...
Lotus corniculatus
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2007
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676650
Pfeiffer
Biosynthesis of flavan 3-ols b ...
Malus domestica, Vitis vinifera
Plant Physiol. Biochem.
44
323-334
2006
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7
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4
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676588
Bogs
Proanthocyanidin synthesis and ...
Vitis vinifera
Plant Physiol.
139
652-663
2005
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654366
Xie
Anthocyanidin reductases from ...
Arabidopsis thaliana, Medicago truncatula
Arch. Biochem. Biophys.
422
91-102
2004
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2
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8
2
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1
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4
-
4
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2
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12
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2
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2
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3
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2
3
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8
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2
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1
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4
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2
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12
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2
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2
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654372
Punyasiri
Flavonoid biosynthesis in the ...
Camellia sinensis
Arch. Biochem. Biophys.
431
22-30
2004
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1
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6
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1
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1
1
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6
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1
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1
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1
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6
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1
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2
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636457
Tanner
Proanthocyanidin biosynthesis ...
Desmodium uncinatum
J. Biol. Chem.
278
31647-31656
2003
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1
1
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15
6
-
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2
3
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8
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1
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1
1
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8
1
1
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1
1
-
2
1
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2
3
1
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16
1
8
-
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4
3
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1
-
2
2
-
8
2
1
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-
2
2
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