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Literature summary for 1.16.1.7 extracted from

  • Kong, D.; Chen, C.; Wu, H.; Li, Y.; Li, J.; Ling, H.Q.
    Sequence diversity and enzyme activity of ferric-chelate reductase LeFRO1 in tomato (2013), J. Genet. Genomics, 40, 565-573.
    View publication on PubMed
Search for more literature for 1.16.1.7

Cloned(Commentary)

Cloned (Comment) Organism
gene LeFRO1, DNA and amino acid sequence determination and analysis from 16 different cultivars, genotyping detects three types of LeFRO1 (LeFRO1MM, LeFRO1Ailsa and LeFRO1Monita) with five amino acid variations at the positions 21, 24, 112, 195 and 582 Solanum lycopersicum

Protein Variants

Protein Variants Comment Organism
A112X modification of this amino acid results in a significant reduction of enzyme activity Solanum lycopersicum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2 Fe(II)-siderophore + NAD+ + H+ Solanum lycopersicum
-
 2 Fe(III)-siderophore + NADH
-
 ?

Organism

Organism UniProt Comment Textmining
Solanum lycopersicum
-
 16 cultivars
-

Source Tissue

Source Tissue Comment Organism Textmining
root
-
 Solanum lycopersicum
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2 Fe(II)-siderophore + NAD+ + H+
-
 Solanum lycopersicum 2 Fe(III)-siderophore + NADH
-
 ?

Synonyms

Synonyms Comment Organism
ferric-chelate reductase
-
 Solanum lycopersicum
FRO1
-
 Solanum lycopersicum

Cofactor

Cofactor Comment Organism Structure
NADH
-
 Solanum lycopersicum

General Information

General Information Comment Organism
additional information Ala112 of LeFRO1 is critical for maintaining the high activity of ferric-chelate reductase, modification of this amino acid results in a significant reduction of enzyme activity. The combination of the amino acid residue Ile at the site 24 with Lys at the site 582 plays a positive role in the enzyme activity of LeFRO1, genotyping, overview Solanum lycopersicum
physiological function ferric-chelate reductase which functions in the reduction of ferric to ferrous iron on root surface is a critical protein for iron homeostasis in strategy I plants. LeFRO1 is a major ferric-chelate reductase involved in iron uptake in tomato Solanum lycopersicum