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Literature summary for 1.15.1.2 extracted from

  • Krätzer, C.; Welte, C.; Dörner, K.; Friedrich, T.; Deppenmeier, U.
    Methanoferrodoxin represents a new class of superoxide reductase containing an iron-sulfur cluster (2011), FEBS J., 278, 442-451.
    View publication on PubMed
Search for more literature for 1.15.1.2

Cloned(Commentary)

Cloned (Comment) Organism
the enzyme is heterologously overexpressed in Escherichia coli Methanosarcina mazei

Metals/Ions

Metals/Ions Comment Organism Structure
Iron the enzyme contains a [Fe(NHis)4(SCys)] site as the catalytic center and an [4Fe–4S] cluster as second prosthetic group that is probably involved in electron transfer to the catalytic center Methanosarcina mazei

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
19000
-
 gel filtration Methanosarcina mazei
20000
-
 x * 20000, SDS-PAGE Methanosarcina mazei

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
reduced rubredoxin + superoxide + 2 H+ Methanosarcina mazei the enzyme may contribute to the protection of cells from oxygen radicals formed by flavoproteins during periodic exposure to oxygen in natural environments rubredoxin + H2O2
-
 ?
reduced rubredoxin + superoxide + 2 H+ Methanosarcina mazei DSM 3647 the enzyme may contribute to the protection of cells from oxygen radicals formed by flavoproteins during periodic exposure to oxygen in natural environments rubredoxin + H2O2
-
 ?

Organism

Organism UniProt Comment Textmining
Methanosarcina mazei Q8PZ62
-
-
Methanosarcina mazei DSM 3647 Q8PZ62
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
reduced cytochrome c + superoxide + 2 H+ oxygen cannot function as an electron acceptor Methanosarcina mazei oxidized cytochrome c + H2O2
-
 ?
reduced cytochrome c + superoxide + 2 H+ oxygen cannot function as an electron acceptor Methanosarcina mazei DSM 3647 oxidized cytochrome c + H2O2
-
 ?
reduced rubredoxin + superoxide + 2 H+ the enzyme may contribute to the protection of cells from oxygen radicals formed by flavoproteins during periodic exposure to oxygen in natural environments Methanosarcina mazei rubredoxin + H2O2
-
 ?
reduced rubredoxin + superoxide + 2 H+ the enzyme may contribute to the protection of cells from oxygen radicals formed by flavoproteins during periodic exposure to oxygen in natural environments Methanosarcina mazei DSM 3647 rubredoxin + H2O2
-
 ?
reduced rubredoxin + superoxide + 2 H+ reduced rubredoxin from Clostridium acetobutylicum Methanosarcina mazei oxidized rubredoxin + H2O2
-
 ?
reduced rubredoxin + superoxide + 2 H+ reduced rubredoxin from Clostridium acetobutylicum Methanosarcina mazei DSM 3647 oxidized rubredoxin + H2O2
-
 ?

Subunits

Subunits Comment Organism
? x * 20000, SDS-PAGE Methanosarcina mazei

Synonyms

Synonyms Comment Organism
cytochrome c–superoxide oxidoreductase
-
 Methanosarcina mazei
MM_0632 locus name Methanosarcina mazei

General Information

General Information Comment Organism
physiological function the enzyme may contributes to the protection of cells from oxygen radicals formed by flavoproteins during periodic exposure to oxygen in natural environments Methanosarcina mazei