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Literature summary for 1.15.1.1 extracted from

  • Iiyama, K.; Chieda, Y.; Lee, J.M.; Kusakabe, T.; Yasunaga-Aoki, C.; Shimizu, S.
    Effect of superoxide dismutase gene inactivation on virulence of Pseudomonas aeruginosa PAO1 toward the silkworm, Bombyx mori (2007), Appl. Environ. Microbiol., 73, 1569-1575.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
subcloning in Escherichia coli, expression of iron-SOD or manganese-SOD in and complementation of an enzyme-deficient double mutant strain Pseudomonas aeruginosa

Protein Variants

Protein Variants Comment Organism
additional information construction of mutants of strain PAO1 lacking manganese-SOD, iron-SOD, or both, the mutants are injected into the hemocoel of Bombyx mori, the virulence decreases in the order: wild-type PAO1, manganese-SOD deficient PAO1, iron-SOD deficient PAO1, and double mutant PAO1, which is avirulent at a dose of 105 cells or less, the virulence of the double mutant can be partially restored by expression of a wild-type enzyme variant, overview Pseudomonas aeruginosa

Metals/Ions

Metals/Ions Comment Organism Structure
Fe2+ iron-SOD variant Pseudomonas aeruginosa
Mn2+ manganese-SOD variant Pseudomonas aeruginosa

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Pseudomonas aeruginosa the enzyme is required for virulence of the organism, e.g. in silkworm Bombyx mori, with iron-SOD being more important, overview ?
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?

Organism

Organism UniProt Comment Textmining
Pseudomonas aeruginosa
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-
-

Source Tissue

Source Tissue Comment Organism Textmining
additional information cell growth in the hemolymph of Bombyx mori Pseudomonas aeruginosa
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Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
Pseudomonas aeruginosa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme is required for virulence of the organism, e.g. in silkworm Bombyx mori, with iron-SOD being more important, overview Pseudomonas aeruginosa ?
-
?

Synonyms

Synonyms Comment Organism
SOD
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Pseudomonas aeruginosa