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Literature summary for 1.15.1.1 extracted from

  • Giles, S.S.; Batinic-Haberle, I.; Perfect, J.R.; Cox, G.M.
    Cryptococcus neoformans mitochondrial superoxide dismutase: an essential link between antioxidant function and high-temperature growth (2005), Eukaryot. Cell, 4, 46-54.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
medicine enzyme deletion mutants are avirulent in a murine model of inhaled cryptococcosis Cryptococcus neoformans

Protein Variants

Protein Variants Comment Organism
additional information strains with mutations in the enzyme gene SOD2 exhibit increased susceptibility to oxidative stress as well as poor growth at elevated temperature Cryptococcus neoformans

Localization

Localization Comment Organism GeneOntology No. Textmining

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Cryptococcus neoformans enzyme Sod2 is a major component of the antioxidant defense system, and adaptation to elevated growth temperatures is also dependent on enzyme activity ?
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?

Organism

Organism UniProt Comment Textmining
Cryptococcus neoformans
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isoform SOD2
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information enzyme Sod2 is a major component of the antioxidant defense system, and adaptation to elevated growth temperatures is also dependent on enzyme activity Cryptococcus neoformans ?
-
?