Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.15.1.1 extracted from

  • Agbas, A.; Hui, D.; Wang, X.; Tek, V.; Zaidi, A.; Michaelis, E.K.
    Activation of brain calcineurin (Cn) by Cu-Zn superoxide dismutase (SOD1) depends on direct SOD1-Cn protein interactions occurring in vitro and in vivo (2007), Biochem. J., 405, 51-59.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.15.1.1

Organism

Organism UniProt Comment Textmining
Bos taurus
-
 isoform SOD1
-
Homo sapiens
-
 isoform SOD1
-

Subunits

Subunits Comment Organism
More isoform SOD1 stabilizes and activates calcineurin in rat brain cytosol by 47% Homo sapiens
More isoform SOD1 stabilizes and activates calcineurin in rat brain cytosol via a nearly 90fold decrease in the KM for p-nitrophenylphosphate. SOD1 prevents the loss of iron and Zn from the active site of calcineurin, possibly by a conformation-dependent interaction. SOD1 also activates human calcineurin by 74% Bos taurus