Literature summary for 1.15.1.1 extracted from

Le Trant, N.; Meshnick, S.R.; Kitchener, K.; Eaton, J.W.; Cerami, A.
Iron-containing superoxide dismutase from Crithidia fasciculata. Purification, characterization, and similarity to Leishmanial and trypanosomal enzymes (1983), J. Biol. Chem., 258, 125-130.

Search for more literature for 1.15.1.1

Inhibitors

Inhibitors	Comment	Organism	Structure
CN-	no inhibition	Crithidia fasciculata
CN-	no inhibition	Leishmania tropica
CN-	no inhibition	Trypanosoma brucei
CN-	no inhibition	Trypanosoma cruzi
H2O2	-	Crithidia fasciculata
H2O2	-	Leishmania tropica
H2O2	-	Trypanosoma brucei
H2O2	-	Trypanosoma cruzi
N3-	-	Crithidia fasciculata
N3-	-	Leishmania tropica
N3-	-	Trypanosoma brucei
N3-	-	Trypanosoma cruzi

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
cytoplasm	-	Trypanosoma brucei	5737	-
cytoplasm	-	Trypanosoma cruzi	5737	-
cytoplasm	-	Leishmania tropica	5737	-
cytoplasm	Fe-SOD	Crithidia fasciculata	5737	-

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Iron	2.7-2.8 mol per mol of enzyme	Trypanosoma brucei
Iron	2.7-2.8 mol per mol of enzyme	Crithidia fasciculata
Iron	2.7-2.8 mol per mol of enzyme	Trypanosoma cruzi
Iron	2.7-2.8 mol per mol of enzyme	Leishmania tropica

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
23000	-	2 * 23000, gel filtration, isoenzyme 2 and 3	Crithidia fasciculata
39000	-	isoenzyme 3, gel filtration	Crithidia fasciculata
43000	-	isoenzyme 2, gel filtration	Crithidia fasciculata

Organism

Organism	UniProt	Comment	Textmining
Crithidia fasciculata	-	Fe-SOD	-
Crithidia fasciculata	-	3 isozymes	-
Crithidia fasciculata Fe-SOD	-	Fe-SOD	-
Leishmania tropica	-	-	-
Trypanosoma brucei	-	-	-
Trypanosoma cruzi	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
3 isoenzymes: 1, 2 and 3	Crithidia fasciculata

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
O2- + H+	-	Trypanosoma brucei	O2 + H2O2	-	?
O2- + H+	-	Crithidia fasciculata	O2 + H2O2	-	?
O2- + H+	-	Trypanosoma cruzi	O2 + H2O2	-	?
O2- + H+	-	Leishmania tropica	O2 + H2O2	-	?
O2- + H+	-	Crithidia fasciculata Fe-SOD	O2 + H2O2	-	?

Subunits

Subunits	Comment	Organism
dimer	2 * 23000, gel filtration, isoenzyme 2 and 3	Crithidia fasciculata

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Release 2023.1 (January 2023)