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Literature summary for 1.14.99.66 extracted from

  • Forneris, F.; Binda, C.; Vanoni, M.A.; Mattevi, A.; Battaglioli, E.
    Histone demethylation catalysed by LSD1 is a flavin-dependent oxidative process (2005), FEBS Lett., 579, 2203-2207 .
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
nucleus
-
Homo sapiens 5634
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
a [histone H3]-N6,N6-dimethyl-L-lysine4 + O2 + 2 H2O Homo sapiens
-
a [histone H3]-L-lysine4 + 2 formaldehyde + 2 H2O2
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens O60341
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
a [histone H3]-N6,N6-dimethyl-L-lysine4 + ferricenium + H2O
-
Homo sapiens a [histone H3]-N6-methyl-L-lysine4 + formaldehyde + ferrocene
-
?
a [histone H3]-N6,N6-dimethyl-L-lysine4 + O2 + 2 H2O
-
Homo sapiens a [histone H3]-L-lysine4 + 2 formaldehyde + 2 H2O2
-
?
a [histone H3]-N6-methyl-L-lysine4 + acceptor + H2O
-
Homo sapiens a [histone H3]-L-lysine4 + formaldehyde + reduced acceptor
-
?
additional information no substrates: dimethylated histone H3 K9 residues Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
KDM1A
-
Homo sapiens
LSD1
-
Homo sapiens
lysine-specific histone demethylase 1A
-
Homo sapiens