Any feedback?
Literature summary for 1.14.99.60 extracted from
- Mouse homologue of coq7/clk-1, longevity gene in Caenorhabditis elegans, is essential for coenzyme Q synthesis, maintenance of mitochondrial integrity, and neurogenesis (2001), Biochem. Biophys. Res. Commun., 289, 463-471 .
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | P97478 | - |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| COQ7 | - |
Mus musculus |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | COQ7-deficient mouse embryos fail to survive beyond embryonic day 10.5, exhibit small-sized body and delayed embryogenesis. COQ7-deficient neuroepithelial cells fail to show the radial arrangement in the developing cerebral wall, aborting neurogenesis at E10.5. The enlarged mitochondria with vesicular cristae and enlarged lysosomes fill with disrupted membranes, which is consistent with mitochondriopathy. COQ7-deficient embryos fail to synthesize CoQ9, but instead yield demethoxyubiquinone 9 | Mus musculus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
