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Literature summary for 1.14.99.60 extracted from

  • Takahashi, M.; Asaumi, S.; Honda, S.; Suzuki, Y.; Nakai, D.; Kuroyanagi, H.; Shimizu, T.; Honda, Y.; Shirasawa, T.
    Mouse coq7/clk-1 orthologue rescued slowed rhythmic behavior and extended life span of clk-1 longevity mutant in Caenorhabditis elegans (2001), Biochem. Biophys. Res. Commun., 286, 534-540 .
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
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Mus musculus 5739
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Organism

Organism UniProt Comment Textmining
Mus musculus P97478
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
proteolytic modification COQ7 is targeted to mitochondria where it is processed to mature form Mus musculus

Source Tissue

Source Tissue Comment Organism Textmining
heart COQ7 is highly expressed in tissues with high energy demand such as heart, muscle, liver, and kidney Mus musculus
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kidney COQ7 is highly expressed in tissues with high energy demand such as heart, muscle, liver, and kidney Mus musculus
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liver COQ7 is highly expressed in tissues with high energy demand such as heart, muscle, liver, and kidney Mus musculus
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muscle COQ7 is highly expressed in tissues with high energy demand such as heart, muscle, liver, and kidney Mus musculus
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Synonyms

Synonyms Comment Organism
COQ7
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Mus musculus

General Information

General Information Comment Organism
physiological function transgenic expression of mouse CoQ7 in Caenorhabditis elegans completely rescues the slowed rhythmic behaviors of Clk-1 mutants such as defecation. In life-span analysis, transgenic expression reverts the extended life span of Clk-1 to a comparable level with wild-type control Mus musculus