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Literature summary for 1.14.99.60 extracted from
- coq7/clk-1 regulates mitochondrial respiration and the generation of reactive oxygen species via coenzyme Q (2004), Aging Cell, 3, 273-281 .
Application
| Application | Comment | Organism |
|---|---|---|
| analysis | development of a mouse model with decreased coenzyme Q, CoQ, transgsgene expression of COQ7/CLK-1. The mice show a concomitant decrease in CoQ9, mitochondrial respiratory enzyme activity and the generation of reactive oxygen species in the mitochondria | Mus musculus |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| mitochondrion | - |
Mus musculus | 5739 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | P97478 | - |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| clk-1 | - |
Mus musculus |
| COQ7 | - |
Mus musculus |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | promoter-driven COQ7/CLK-1 expression providing low levels of transgene expression rescues COQ7-deficient mice from embryonic lethality. The mice show a concomitant decrease in CoQ9, mitochondrial respiratory enzyme activity and the generation of reactive oxygen species in the mitochondria | Mus musculus |
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