BRENDA - Enzyme Database show
show all sequences of 1.14.99.58

Homologues of neisserial heme oxygenase in gram-negative bacteria degradation of heme by the product of the pigA gene of Pseudomonas aeruginosa

Ratliff, M.; Zhu, W.; Deshmukh, R.; Wilks, A.; Stojiljkovic, I.; J. Bacteriol. 183, 6394-6403 (2001)

Data extracted from this reference:

Cloned(Commentary)
Commentary
Organism
expressed in a Neisseria meningitidis HemO deletion mutant
Pseudomonas aeruginosa
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
protoheme + reduced acceptor + O2
Pseudomonas aeruginosa
-
biliverdin-IX-beta + CO + Fe2+ + acceptor + H2O
-
-
?
protoheme + reduced acceptor + O2
Pseudomonas aeruginosa
-
biliverdin-IX-delta + CO + Fe2+ + acceptor + H2O
-
-
?
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Pseudomonas aeruginosa
-
-
-
Purification (Commentary)
Commentary
Organism
-
Pseudomonas aeruginosa
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
protoheme + reduced acceptor + O2
-
742771
Pseudomonas aeruginosa
biliverdin-IX-beta + CO + Fe2+ + acceptor + H2O
-
-
-
?
protoheme + reduced acceptor + O2
-
742771
Pseudomonas aeruginosa
biliverdin-IX-delta + CO + Fe2+ + acceptor + H2O
-
-
-
?
Subunits
Subunits
Commentary
Organism
?
x * 25000, SDS-PAGE
Pseudomonas aeruginosa
Cofactor
Cofactor
Commentary
Organism
Structure
heme
-
Pseudomonas aeruginosa
Cloned(Commentary) (protein specific)
Commentary
Organism
expressed in a Neisseria meningitidis HemO deletion mutant
Pseudomonas aeruginosa
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
heme
-
Pseudomonas aeruginosa
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
protoheme + reduced acceptor + O2
Pseudomonas aeruginosa
-
biliverdin-IX-beta + CO + Fe2+ + acceptor + H2O
-
-
?
protoheme + reduced acceptor + O2
Pseudomonas aeruginosa
-
biliverdin-IX-delta + CO + Fe2+ + acceptor + H2O
-
-
?
Purification (Commentary) (protein specific)
Commentary
Organism
-
Pseudomonas aeruginosa
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
protoheme + reduced acceptor + O2
-
742771
Pseudomonas aeruginosa
biliverdin-IX-beta + CO + Fe2+ + acceptor + H2O
-
-
-
?
protoheme + reduced acceptor + O2
-
742771
Pseudomonas aeruginosa
biliverdin-IX-delta + CO + Fe2+ + acceptor + H2O
-
-
-
?
Subunits (protein specific)
Subunits
Commentary
Organism
?
x * 25000, SDS-PAGE
Pseudomonas aeruginosa
Other publictions for EC 1.14.99.58
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
742894
Mourino
Metabolite-driven regulation ...
Pseudomonas aeruginosa
J. Biol. Chem.
291
20503-20515
2016
-
-
1
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2
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2
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1
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1
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2
1
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726833
Gisk
Variable composition of heme o ...
Pseudomonas aeruginosa, Pseudomonas aeruginosa KT 2240, Pseudomonas fluorescens, Pseudomonas fluorescens Pf-5, Pseudomonas mendocina, Pseudomonas mendocina YMP, Pseudomonas putida, Pseudomonas putida KT 2240, Pseudomonas syringae pv. tomato, Pseudomonas syringae pv. tomato DC3000
Arch. Microbiol.
194
597-606
2012
-
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5
-
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-
6
-
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30
-
16
-
-
5
-
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48
-
5
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3
5
-
6
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9
10
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6
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30
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9
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48
-
6
-
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3
6
-
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-
742839
Barker
Metabolic flux of extracellul ...
Pseudomonas aeruginosa
J. Biol. Chem.
287
18342-18350
2012
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1
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2
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1
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2
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-
-
-
-
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-
1
1
-
-
-
692400
Barkovits
Expression of the phytochrome ...
Pseudomonas aeruginosa
FEMS Microbiol. Lett.
80
160-168
2008
1
-
1
-
1
-
-
-
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1
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1
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1
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1
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1
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1
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1
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1
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680357
Rodríguez
The hydrogen-bonding network i ...
Pseudomonas aeruginosa
J. Am. Chem. Soc.
129
11730-11742
2007
-
-
-
1
1
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1
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1
1
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681311
Furci
Inhibition of the bacterial he ...
Pseudomonas aeruginosa
J. Med. Chem.
50
3804-3813
2007
-
1
-
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-
13
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1
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1
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1
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13
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1
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678146
Bhakta
The mechanism of heme transfer ...
Pseudomonas aeruginosa
Biochemistry
45
11642-11649
2006
-
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4
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1
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1
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4
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678184
Rodríguez
Backbone NMR assignments and H ...
Pseudomonas aeruginosa
Biochemistry
45
4578-4592
2006
-
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1
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1
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659407
Wegele
The heme oxygenase(s)-phytochr ...
Pseudomonas aeruginosa
J. Biol. Chem.
279
45791-45802
2004
-
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1
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2
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1
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1
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1
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1
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1
1
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742737
Fujii
Essential amino acid residues ...
Pseudomonas aeruginosa
J. Am. Chem. Soc.
126
4466-4467
2004
-
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1
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8
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2
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1
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661923
Caignan
Oxidation of heme to beta- and ...
Pseudomonas aeruginosa
J. Am. Chem. Soc.
124
14879-14892
2002
-
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3
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1
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742771
Ratliff
Homologues of neisserial heme ...
Pseudomonas aeruginosa
J. Bacteriol.
183
6394-6403
2001
-
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1
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2
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1
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1
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1
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