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Literature summary for 1.14.99.48 extracted from

  • Matsui, T.; Nambu, S.; Ono, Y.; Goulding, C.W.; Tsumoto, K.; Ikeda-Saito, M.
    Heme degradation by Staphylococcus aureus IsdG and IsdI liberates formaldehyde rather than carbon monoxide (2013), Biochemistry, 52, 3025-3027.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Staphylococcus aureus
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-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the primary C1 product of the both isoform IsdG and IsdH is formaldehyde. In the mechanism, one meso carbon atom of the porphyrin ring is liberated primarily as formaldehyde Staphylococcus aureus ?
-
?
protoheme + 5 reduced acceptor + 4 O2
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Staphylococcus aureus 15-oxo-beta-bilirubin + Fe2+ + formaldehyde + 5 acceptor + 4 H2O
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?
protoheme + 5 reduced acceptor + 4 O2
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Staphylococcus aureus 5-oxo-delta-bilirubin + Fe2+ + formaldehyde + 5 acceptor + 4 H2O
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?

Synonyms

Synonyms Comment Organism
isdG
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Staphylococcus aureus
isdI
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Staphylococcus aureus