BRENDA - Enzyme Database show
show all sequences of 1.14.99.4

Cisplatin induced toxicity in rat tissues: the protective effect of Lisosan G

Longo, V.; Gervasi, P.; Lubrano, V.; Food Chem. Toxicol. 49, 233-237 (2011)

Data extracted from this reference:

Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
microsome
17beta-progesterone hydroxylase
Rattus norvegicus
-
-
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Rattus norvegicus
-
-
-
Rattus norvegicus Wistar
-
-
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
liver
-
Rattus norvegicus
-
testis
-
Rattus norvegicus
-
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
microsome
17beta-progesterone hydroxylase
Rattus norvegicus
-
-
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
liver
-
Rattus norvegicus
-
testis
-
Rattus norvegicus
-
General Information
General Information
Commentary
Organism
additional information
Lisosan G protects the testicular 17alpha-progesterone hydroxylase activity and increases the plasma testosterone level compared to animals treated only with cisplatin
Rattus norvegicus
General Information (protein specific)
General Information
Commentary
Organism
additional information
Lisosan G protects the testicular 17alpha-progesterone hydroxylase activity and increases the plasma testosterone level compared to animals treated only with cisplatin
Rattus norvegicus
Other publictions for EC 1.14.99.4
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
715071
Longo
Cisplatin induced toxicity in ...
Rattus norvegicus, Rattus norvegicus Wistar
Food Chem. Toxicol.
49
233-237
2011
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166
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1
1
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659812
Lenasi
Specific interactions of stero ...
Rhizopus stolonifer
J. Steroid Biochem. Mol. Biol.
91
273-284
2004
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1
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438220
Berrie
Purification and characterizat ...
Streptomyces roseochromogenes
Biochem. Soc. Trans.
25
18S
1997
1
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1
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1
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438221
Hua
cDNA cloning, heterologous exp ...
Mus musculus, Oryctolagus cuniculus, Rattus norvegicus
Arch. Biochem. Biophys.
340
208-214
1997
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1
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1
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7
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7
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7
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438219
Straub
Differential effects of mutati ...
Chlorocebus aethiops
Biochemistry
33
8029-8034
1994
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438217
Schlenk
Channel catfish liver monooxyg ...
Ictalurus punctatus, Oncorhynchus mykiss, Oryctolagus cuniculus, Sus scrofa
Biochem. Pharmacol.
45
217-221
1993
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2
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1
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4
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4
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6
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6
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438218
Straub
Hydrophobic side chain require ...
Chlorocebus aethiops
Arch. Biochem. Biophys.
306
521-527
1993
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438216
Rahim
Mechanisms of steroid oxidatio ...
Amorphotheca resinae, Ilyonectria destructans, Ilyonectria destructans ACC 11011
J. Biol. Chem.
241
3615-3623
1966
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4
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3
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13
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