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Literature summary for 1.14.99.38 extracted from

  • Bauman, D.R.; Bitmansour, A.D.; McDonald, J.G.; Thompson, B.M.; Liang, G.; Russell, D.W.
    25-Hydroxycholesterol secreted by macrophages in response to Toll-like receptor activation suppresses immunoglobulin A production (2009), Proc. Natl. Acad. Sci. USA, 106, 16764-16769.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.14.99.38

Activating Compound

Activating Compound Comment Organism Structure
25-hydroxycholesterol
-
 Mus musculus
Kdo2-lipid A
-
 Mus musculus
additional information incubation with LPS derived from Escherichia coli or Salmonella enterica induces CH25H mRNA Mus musculus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
33000
-
 determined by SDS-PAGE and Western Blot analysis Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
cholesterol + AH2 + O2 Mus musculus
-
 25-hydroxycholesterol + A + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Mus musculus
-
colon
-
 Mus musculus
-
heart
-
 Mus musculus
-
kidney
-
 Mus musculus
-
liver
-
 Mus musculus
-
lung
-
 Mus musculus
-
macrophage
-
 Mus musculus
-
muscle
-
 Mus musculus
-
skin
-
 Mus musculus
-
small intestine
-
 Mus musculus
-
spleen
-
 Mus musculus
-
thymus
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
cholesterol + AH2 + O2
-
 Mus musculus 25-hydroxycholesterol + A + H2O
-
 ?

Synonyms

Synonyms Comment Organism
CH25A
-
 Mus musculus
cholesterol 25-hydroxylase
-
 Mus musculus