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Literature summary for 1.14.99.38 extracted from

  • Papassotiropoulos, A.; Lambert, J.C.; Wavrant-De Vrieze, F.; Wollmer, M.A.; von der Kammer, H.; Streffer, J.R.; Maddalena, A.; Huynh, K.D.; Wolleb, S.; Lutjohann, D.; Schneider, B.; Thal, D.R.; Grimaldi, L.M.; Tsolaki, M.; Kapaki, E.; Ravid, R.; Konietzko, U.; Hegi, T.; Pasch, T.; Jung, H.; Braak, H.
    Cholesterol 25-hydroxylase on chromosome 10q is a susceptibility gene for sporadic Alzheimers disease (2005), Neurodegener. Dis., 2, 233-241.
    View publication on PubMed

Application

Application Comment Organism
medicine patients with Alzheimer’s disease show high expression of cholesterol 25-hydroxylase gene in specifically vulnerable brain regions. The common enzyme haplotype CH25Hchi4 is a putative susceptibility factor for sporadic Alzheimer’s disease Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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patients with Alzheimer’s disease
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