Cloned (Comment) | Organism |
---|---|
- |
Homo sapiens |
- |
Saccharomyces cerevisiae |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
eukaryotic translation initiation factor eIF-5A deoxyhypusine + O2 + AH2 | Homo sapiens | - |
eukaryotic translation initiation factor eIF-5A hypusine + H2O + A | - |
? | |
eukaryotic translation initiation factor eIF-5A deoxyhypusine + O2 + AH2 | Saccharomyces cerevisiae | - |
eukaryotic translation initiation factor eIF-5A hypusine + H2O + A | - |
? | |
additional information | Saccharomyces cerevisiae | following mutants of human eIF-5A are substrates for DOHH - K47A, K47R, G49A, G52A, K55A, P74A, L91A and L101A | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Saccharomyces cerevisiae | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
- |
Saccharomyces cerevisiae |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
eukaryotic translation initiation factor eIF-5A deoxyhypusine + O2 + AH2 | - |
Homo sapiens | eukaryotic translation initiation factor eIF-5A hypusine + H2O + A | - |
? | |
eukaryotic translation initiation factor eIF-5A deoxyhypusine + O2 + AH2 | - |
Saccharomyces cerevisiae | eukaryotic translation initiation factor eIF-5A hypusine + H2O + A | - |
? | |
additional information | following mutants of human eIF-5A are substrates for DOHH - K47A, K47R, G49A, G52A, K55A, P74A, L91A and L101A | Saccharomyces cerevisiae | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
deoxyhypusine hydroxylase | - |
Homo sapiens |
deoxyhypusine hydroxylase | - |
Saccharomyces cerevisiae |
DOHH | - |
Homo sapiens |
hDOHH | - |
Saccharomyces cerevisiae |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
combined deoxyhypusine synthase and hydroxylase assay | Homo sapiens |
37 | - |
combined deoxyhypusine synthase and hydroxylase assay | Saccharomyces cerevisiae |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8.5 | - |
combined deoxyhypusine synthase and hydroxylase assay | Homo sapiens |
8.5 | - |
combined deoxyhypusine synthase and hydroxylase assay | Saccharomyces cerevisiae |