Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-(2-hydroxy-5-methylphenyl)-1,3-thiazole-4-carboxylic acid | inhibition in vitro and in cells | Cricetulus griseus | |
2-(2-hydroxy-5-methylphenyl)-4,5-dihydro-1,3-thiazole-4-carboxylic acid | inhibition in vitro and in cells | Cricetulus griseus | |
2-(2-hydroxy-5-methylphenyl)-4,5-dihydro-1,3-thiazole-4-carboxylic acid | inhibition in vitro and in cells | Homo sapiens | |
mimosine | reversible inhibition | Cricetulus griseus | |
mimosine | S-isomer, complete inhibition at 0.2 mM in LAZ463 cells | Homo sapiens | |
additional information | no inhibition by S-isomers of kojic acid, 3-pyridylalanine, 4-pyridylalanine at 0.3 mM in vitro and at 0.2 mM in cells, no inhibition by 2-(2-aminophenyl)-1,3-thiazole-4-carboxylic acid at 0.4 mM in cells | Cricetulus griseus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Cricetulus griseus | - |
- |
- |
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
N'-(4-aminobutyl)lysine + electron donor + O2 | i.e. deoxyhypusine | Cricetulus griseus | N'-(4-amino-2-hydroxybutyl)lysine + oxidized electron donor + H2O | i.e. hypusine | ? | |
N'-(4-aminobutyl)lysine + electron donor + O2 | i.e. deoxyhypusine | Homo sapiens | N'-(4-amino-2-hydroxybutyl)lysine + oxidized electron donor + H2O | i.e. hypusine | ? |