BRENDA - Enzyme Database show
show all sequences of 1.14.99.19

Biosynthesis of plasmalogens by the microsomal fraction of Fischer R-3259 sarcoma. Influence of specific 2-acyl chains on the desaturation of 1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine

Wykle, R.L.; Schremmer, J.M.; Biochemistry 18, 3512-3517 (1979)

Data extracted from this reference:

Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
microsome
-
Rattus norvegicus
-
-
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Rattus norvegicus
-
-
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
sarcoma cell
Fischer R-3259 sarcoma
Rattus norvegicus
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1-hexadecyl-2-acyl glycero-3-phosphoethanolamine + NADH + O2
in situ in the microsomes via acylation of 1-hexadecyl-glycero-3-phosphoethanolamine
438315
Rattus norvegicus
?
-
-
-
?
additional information
no selectivity of the desaturase for specific acyl chains
438315
Rattus norvegicus
?
-
-
-
-
Cofactor
Cofactor
Commentary
Organism
Structure
NADH
-
Rattus norvegicus
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NADH
-
Rattus norvegicus
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
microsome
-
Rattus norvegicus
-
-
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
sarcoma cell
Fischer R-3259 sarcoma
Rattus norvegicus
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1-hexadecyl-2-acyl glycero-3-phosphoethanolamine + NADH + O2
in situ in the microsomes via acylation of 1-hexadecyl-glycero-3-phosphoethanolamine
438315
Rattus norvegicus
?
-
-
-
?
additional information
no selectivity of the desaturase for specific acyl chains
438315
Rattus norvegicus
?
-
-
-
-
Other publictions for EC 1.14.99.19
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
727110
Watschinger
Orphan enzymes in ether lipid ...
Homo sapiens
Biochimie
95
59-65
2013
-
-
-
-
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1
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1
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2
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3
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1
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1
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3
-
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2
2
-
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-
438318
Das
A novel chemical synthesis of ...
Rattus norvegicus
J. Lipid Res.
37
2706-2714
1996
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1
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1
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2
1
1
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1
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1
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1
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1
2
1
1
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1
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438319
Blank
Plasmanylethanolamine D1-desat ...
Mesocricetus auratus, Mus musculus, Oryctolagus cuniculus, Rattus norvegicus
Methods Enzymol.
209
390-396
1992
4
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-
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1
4
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4
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4
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6
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8
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4
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8
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4
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8
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1
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4
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4
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6
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8
-
4
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438316
Weber
Formation of ether lipids and ...
Mus musculus, Rattus norvegicus
Biochim. Biophys. Acta
711
197-207
1982
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-
-
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1
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3
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4
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1
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2
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4
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438315
Wykle
Biosynthesis of plasmalogens b ...
Rattus norvegicus
Biochemistry
18
3512-3517
1979
-
-
-
-
-
-
-
-
1
-
-
-
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1
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1
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1
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1
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1
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1
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2
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438317
Baumann
On the substrate specificity o ...
Rattus norvegicus
Biochem. Biophys. Res. Commun.
66
717-724
1975
-
-
-
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1
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1
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1
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2
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438312
Paltauf
Enzymatic synthesis of plasmal ...
Mesocricetus auratus
J. Biol. Chem.
248
1609-1615
1973
1
-
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-
-
10
-
1
1
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1
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1
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1
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1
1
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3
-
1
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1
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2
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1
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2
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10
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1
1
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1
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1
1
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3
-
1
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1
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438314
Lee
Dietary control of stearyl CoA ...
Rattus norvegicus
Biochem. Biophys. Res. Commun.
55
574-579
1973
1
-
-
-
-
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-
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1
1
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1
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1
2
1
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1
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1
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438313
Wykle
Evidence for a mixed function ...
Rattus norvegicus
J. Biol. Chem.
247
5442-5447
1972
2
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-
1
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1
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1
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1
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1
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1
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1
1
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1
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3
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2
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3
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1
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1
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1
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1
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1
1
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1
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