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Literature summary for 1.14.99.12 extracted from

  • Fan, L.Q.; You, L.; Brown-Borg, H.; Brown, S.; Edwards, R.J.; Corton, J.C.
    Regulation of phase I and phase II steroid metabolism enzymes by PPARa activators (2004), Toxicology, 204, 109-121.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
androst-4-ene-3,17-dione + AH2 + O2 Rattus norvegicus enzyme levels increase after exposure of rats to di-n-butyl phthalate 3-oxo-13,17-secoandrost-4-ene-17,13alpha-lactone + A + H2O
-
?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
androst-4-ene-3,17-dione + AH2 + O2
-
Rattus norvegicus 3-oxo-13,17-secoandrost-4-ene-17,13alpha-lactone + A + H2O
-
?
androst-4-ene-3,17-dione + AH2 + O2 enzyme levels increase after exposure of rats to di-n-butyl phthalate Rattus norvegicus 3-oxo-13,17-secoandrost-4-ene-17,13alpha-lactone + A + H2O
-
?