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Literature summary for 1.14.99.1 extracted from
- Bacterial and algal orthologs of prostaglandin H2 synthase novel insights into the evolution of an integral membrane protein (2015), Biochim. Biophys. Acta, 1848, 83-94 .
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| membrane | - |
Ovis aries | 16020 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| arachidonate + reduced acceptor + O2 | Ovis aries | - |
prostaglandin H2 + acceptor + H2O | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Ovis aries | P05979 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| arachidonate + reduced acceptor + O2 | - |
Ovis aries | prostaglandin H2 + acceptor + H2O | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PGHS-1 | isoform | Ovis aries |
| prostaglandin H2 synthase | - |
Ovis aries |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| heme | - |
Ovis aries | |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | the bi-functional enzyme with cyclooxygenase and peroxidase activities plays a central role in the inflammatory response, pain, and blood clotting | Ovis aries |
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Release 2023.1 (January 2023)
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