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Literature summary for 1.14.99.1 extracted from

  • Enami, Y.; Bandi, S.; Kapoor, S.; Krohn, N.; Joseph, B.; Gupta, S.
    Hepatic stellate cells promote hepatocyte engraftment in rat liver after prostaglandin-endoperoxide synthase inhibition (2009), Gastroenterology, 136, 2356-2364.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
celecoxib
-
Rattus norvegicus
naproxen
-
Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus P35355
-
-
Rattus norvegicus Q63921
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
arachidonate + AH2 + O2
-
Rattus norvegicus prostaglandin H2 + A + H2O
-
?

Synonyms

Synonyms Comment Organism
prostaglandin-endoperoxide synthase 1 isoform Rattus norvegicus
prostaglandin-endoperoxide synthase 2 isoform Rattus norvegicus
PTGS1 isoform Rattus norvegicus
PTGS2 isoform Rattus norvegicus

Expression

Organism Comment Expression
Rattus norvegicus transplantation of hepatocytes induces hepatic expression of prostaglandin-endoperoxide synthase isoform 1 (5fold) up
Rattus norvegicus transplantation of hepatocytes induces hepatic expression of prostaglandin-endoperoxide synthase isoform 2 (2.8fold) up