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Literature summary for 1.14.19.9 extracted from

  • Bitto, E.; Huang, Y.; Bingman, C.A.; Singh, S.; Thorson, J.S.; Phillips, G.N. Jr.
    The structure of flavin-dependent tryptophan 7-halogenase RebH (2008), Proteins, 70, 289-293.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Lentzea aerocolonigenes

Crystallization (Commentary)

Crystallization (Comment) Organism
hanging drop method, structural analysis of RebH in its apo-form as well as in a complex with both tryptophan and FAD Lentzea aerocolonigenes

Organism

Organism UniProt Comment Textmining
Lentzea aerocolonigenes Q8KHZ8
-
-

Purification (Commentary)

Purification (Comment) Organism
recombinant enzyme Lentzea aerocolonigenes

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-tryptophan + FADH2 + Br- + O2 + H+
-
Lentzea aerocolonigenes 7-bromo-L-tryptophan + FAD + H2O
-
?
L-tryptophan + FADH2 + Cl- + O2 + H+
-
Lentzea aerocolonigenes 7-chloro-L-tryptophan + FAD + H2O
-
?

Synonyms

Synonyms Comment Organism
RebH
-
Lentzea aerocolonigenes

Cofactor

Cofactor Comment Organism Structure
FADH2
-
Lentzea aerocolonigenes