BRENDA - Enzyme Database show
show all sequences of 1.14.19.8

Product-mediated regulation of pentalenolactone biosynthesis in Streptomyces species by the MarR/SlyA family activators PenR and PntR

Zhu, D.; Wang, Y.; Zhang, M.; Ikeda, H.; Deng, Z.; Cane, D.E.; J. Bacteriol. 195, 1255-1266 (2013)

Data extracted from this reference:

Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
pentalenolactone F + O2 + NADPH + H+
Streptomyces exfoliatus
-
pentalenolactone + NADP+ + H2O
-
-
?
pentalenolactone F + O2 + NADPH + H+
Streptomyces arenae
-
pentalenolactone + NADP+ + H2O
-
-
?
pentalenolactone F + O2 + NADPH + H+
Streptomyces exfoliatus UC5319
-
pentalenolactone + NADP+ + H2O
-
-
?
pentalenolactone F + O2 + NADPH + H+
Streptomyces arenae TUE469
-
pentalenolactone + NADP+ + H2O
-
-
?
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Streptomyces arenae
-
-
-
Streptomyces arenae TUE469
-
-
-
Streptomyces exfoliatus
-
-
-
Streptomyces exfoliatus UC5319
-
-
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
pentalenolactone F + O2 + NADPH + H+
-
727767
Streptomyces exfoliatus
pentalenolactone + NADP+ + H2O
-
-
-
?
pentalenolactone F + O2 + NADPH + H+
-
727767
Streptomyces arenae
pentalenolactone + NADP+ + H2O
-
-
-
?
pentalenolactone F + O2 + NADPH + H+
-
727767
Streptomyces exfoliatus UC5319
pentalenolactone + NADP+ + H2O
-
-
-
?
pentalenolactone F + O2 + NADPH + H+
-
727767
Streptomyces arenae TUE469
pentalenolactone + NADP+ + H2O
-
-
-
?
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
pentalenolactone F + O2 + NADPH + H+
Streptomyces exfoliatus
-
pentalenolactone + NADP+ + H2O
-
-
?
pentalenolactone F + O2 + NADPH + H+
Streptomyces arenae
-
pentalenolactone + NADP+ + H2O
-
-
?
pentalenolactone F + O2 + NADPH + H+
Streptomyces exfoliatus UC5319
-
pentalenolactone + NADP+ + H2O
-
-
?
pentalenolactone F + O2 + NADPH + H+
Streptomyces arenae TUE469
-
pentalenolactone + NADP+ + H2O
-
-
?
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
pentalenolactone F + O2 + NADPH + H+
-
727767
Streptomyces exfoliatus
pentalenolactone + NADP+ + H2O
-
-
-
?
pentalenolactone F + O2 + NADPH + H+
-
727767
Streptomyces arenae
pentalenolactone + NADP+ + H2O
-
-
-
?
pentalenolactone F + O2 + NADPH + H+
-
727767
Streptomyces exfoliatus UC5319
pentalenolactone + NADP+ + H2O
-
-
-
?
pentalenolactone F + O2 + NADPH + H+
-
727767
Streptomyces arenae TUE469
pentalenolactone + NADP+ + H2O
-
-
-
?
Expression
Organism
Commentary
Expression
Streptomyces arenae
transcription is activated by the PntR protein
up
Streptomyces exfoliatus
transcription is activated by the PenR protein
up
Expression (protein specific)
Organism
Commentary
Expression
Streptomyces arenae
transcription is activated by the PntR protein
up
Streptomyces exfoliatus
transcription is activated by the PenR protein
up
Other publictions for EC 1.14.19.8
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [C]
Temperature Range [C]
Temperature Stability [C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [C] (protein specific)
Temperature Range [C] (protein specific)
Temperature Stability [C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
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1
1
8
-
-
7
-
1
-
-
-
2
-
-
1
1
-
-
-
-
2
1
1
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-
7
1
-
-
2
-
-
-
-
-
1
2
1
8
-
-
-
-
7
-
1
-
-
-
-
-
1
-
-
-
-
2
1
1
-
-
7
1
-
-
-
-
2
2
-
7
7
727767
Zhu
Product-mediated regulation of ...
Streptomyces arenae, Streptomyces arenae TUE469, Streptomyces exfoliatus, Streptomyces exfoliatus UC5319
J. Bacteriol.
195
1255-1266
2013
-
-
-
-
-
-
-
-
-
-
-
4
-
9
-
-
-
-
-
-
-
-
4
-
-
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-
-
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4
-
-
-
-
-
-
-
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4
-
-
-
-
-
-
-
-
-
2
-
-
2
-
-
719654
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133
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2011
-
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2
-
-
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-
2
-
-
-
-
-
15
-
-
2
-
-
-
-
-
4
2
-
-
-
2
-
-
-
2
-
-
-
-
-
2
2
-
-
-
-
-
-
2
-
-
-
-
-
-
-
2
-
-
-
-
4
2
-
-
-
2
-
-
-
-
-
-
-
-
-
-
718843
Tetzlaff
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Streptomyces avermitilis
Biochemistry
45
6179-6186
2006
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
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-
-
-
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