Literature summary for 1.14.19.70 extracted from

Brengel, C.; Thomann, A.; Schifrin, A.; Allegretta, G.; Kamal, A.A.M.; Haupenthal, J.; Schnorr, I.; Cho, S.H.; Franzblau, S.G.; Empting, M.; Eberhard, J.; Hartmann, R.W.
Biophysical screening of a focused library for the discovery of CYP121 inhibitors as novel antimycobacterials (2017), ChemMedChem, 12, 1616-1626 .

Search for more literature for 1.14.19.70

Application

Application	Comment	Organism
medicine	CYP121 is a potential target for the treatment of Mycobacterium tuberculosis infections	Mycobacterium tuberculosis
pharmacology	CYP121 is a potential target for the treatment of Mycobacterium tuberculosis infections	Mycobacterium tuberculosis

Inhibitors

Inhibitors	Comment	Organism	Structure
additional information	biophysical screening procedure employing a focused library of privileged scaffolds, which ultimately lead to the discovery of novel CYP121 inhibitors	Mycobacterium tuberculosis

Organism

Organism	UniProt	Comment	Textmining
Mycobacterium tuberculosis	P9WPP7	-	-
Mycobacterium tuberculosis H37Rv	P9WPP7	-	-

Synonyms

Synonyms	Comment	Organism
CYP121	-	Mycobacterium tuberculosis

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)