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Literature summary for 1.14.19.65 extracted from

  • Ikezawa, N.; Iwasa, K.; Sato, F.
    CYP719A subfamily of cytochrome P450 oxygenases and isoquinoline alkaloid biosynthesis in Eschscholzia californica (2009), Plant Cell Rep., 28, 123-133.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
methyl jasmonate
-
Eschscholzia californica

Cloned(Commentary)

Cloned (Comment) Organism
into the pT7Blue T-vector for sequencing, and subcloned into a yeast expression vector Eschscholzia californica

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(S)-scoulerine + [reduced NADPH-hemoprotein reductase] + O2 Eschscholzia californica
-
(S)-cheilanthifoline + [oxidized NADPH-hemoprotein reductase] + H2O
-
?

Organism

Organism UniProt Comment Textmining
Eschscholzia californica
-
-
-

Purification (Commentary)

Purification (Comment) Organism
yeast microsomal fractions are prepared Eschscholzia californica

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(S)-scoulerine + [reduced NADPH-hemoprotein reductase] + O2
-
Eschscholzia californica (S)-cheilanthifoline + [oxidized NADPH-hemoprotein reductase] + H2O
-
?

Synonyms

Synonyms Comment Organism
cheilanthifoline synthase
-
Eschscholzia californica
CYP719A5
-
Eschscholzia californica

Expression

Organism Comment Expression
Eschscholzia californica methyl jasmonate induces the expression of CYP719A genes in seedlings up