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Literature summary for 1.14.19.47 extracted from

  • Huang, Y.S.; Chaudhary, S.; Thurmond, J.M.; Bobik, E.G.; Yuan, L.; Chan, G.M.; Kirchner, S.J.; Mukerji, P.; Knutzon, D.S.
    Cloning of DELAT12- and DELTA6-desaturases from Mortierella alpina and recombinant production of gamma-linolenic acid in Saccharomyces cerevisiae (1999), Lipids, 34, 649-659.
    View publication on PubMed
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Cloned(Commentary)

Cloned (Comment) Organism
expressed in Saccharomyces cerevisiae Mortierella alpina

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
alpha-linolenoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+ Mortierella alpina
-
 stearidonoyl-[glycerolipid] + ferricytochrome b5 + H2O
-
 ?
linoleoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+ Mortierella alpina
-
 gamma-linolenoyl-[glycerolipid] + ferricytochrome b5 + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Mortierella alpina Q9UVV3
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
alpha-linolenoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+
-
 Mortierella alpina stearidonoyl-[glycerolipid] + ferricytochrome b5 + H2O
-
 ?
linoleoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+
-
 Mortierella alpina gamma-linolenoyl-[glycerolipid] + ferricytochrome b5 + H2O
-
 ?

Synonyms

Synonyms Comment Organism
DELTA6-desaturase
-
 Mortierella alpina
DES6
-
 Mortierella alpina

Cofactor

Cofactor Comment Organism Structure
cytochrome b5
-
 Mortierella alpina