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Literature summary for 1.14.19.31 extracted from

  • Park, H.G.; Park, W.J.; Kothapalli, K.S.; Brenna, J.T.
    The fatty acid desaturase 2 (FADS2) gene product catalyzes DELTA4 desaturation to yield n-3 docosahexaenoic acid and n-6 docosapentaenoic acid in human cells (2015), FASEB J., 29, 3911-3919 .
    View publication on PubMedView publication on EuropePMC
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Cloned(Commentary)

Cloned (Comment) Organism
expression in MCF-7 human breast cancer cells. MCF-7 cells stably expressing FADS1 and FADS2 Papio anubis

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion the localization of FADS2 in mitochondria, supports the involvement of this organelle in long-chain polyunsaturated fatty acid synthesis Papio anubis 5739
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Organism

Organism UniProt Comment Textmining
Papio anubis B8R1K0
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Source Tissue

Source Tissue Comment Organism Textmining
liver
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 Papio anubis
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the FADS2 classical transcript mediates direct DELTA4-desaturation of 22:5n-3 to 22:6n-3 (docosahexaenoic acid) and of 22:4n-6 to 22:5n-6. The evidence supports trifunctionality of FADS2. The classical transcript shows DELTA6, DELTA8, and DELTA4 activities in mammals Papio anubis ?
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 ?

Synonyms

Synonyms Comment Organism
FADS2
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 Papio anubis