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Literature summary for 1.14.19.17 extracted from

  • Garton, S.; Michaelson, L.V.; Beaudoin, F.; Beale, M.H.; Napier, J.A.
    The dihydroceramide desaturase is not essential for cell viability in Schizosaccharomyces pombe (2003), FEBS Lett., 538, 192-196.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Saccharomyces cerevisiae strain w303-1a Schizosaccharomyces pombe

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
dihydroceramide + ferrocytochrome b5 + O2 + H+ Schizosaccharomyces pombe
-
(4E)-sphing-4-enine ceramide + ferricytochrome b5 + H2O
-
?

Organism

Organism UniProt Comment Textmining
Schizosaccharomyces pombe O59715
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dihydroceramide + ferrocytochrome b5 + O2 + H+
-
Schizosaccharomyces pombe (4E)-sphing-4-enine ceramide + ferricytochrome b5 + H2O
-
?
additional information the enzyme does not recognise fatty acids and trihydroxylated sphingoid long-chain bases as substrate Schizosaccharomyces pombe ?
-
?

Synonyms

Synonyms Comment Organism
dehydroceramide desaturase
-
Schizosaccharomyces pombe
dihydroceramide DELTA4-desaturase
-
Schizosaccharomyces pombe
SPBC3B8.07c
-
Schizosaccharomyces pombe

Cofactor

Cofactor Comment Organism Structure
cytochrome b5
-
Schizosaccharomyces pombe

General Information

General Information Comment Organism
physiological function the enzyme has no effect on cell viability Schizosaccharomyces pombe