Cloned (Comment) | Organism |
---|---|
gene SCD, semiquantitative and quantitative RT-PCR enzyme expression analysis | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
stearoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+ | Homo sapiens | - |
oleoyl-CoA + 2 ferricytochrome b5 + 2 H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | O00767 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
extravillous trophoblast | - |
Homo sapiens | - |
HTR8/SVneo cell | EVT cell line | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
stearoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+ | - |
Homo sapiens | oleoyl-CoA + 2 ferricytochrome b5 + 2 H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
SCD1 | - |
Homo sapiens |
stearoyl-CoA desaturase-1 | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
cytochrome b5 | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | oleic acid stimulation of motility of human extravillous trophoblast cells is mediated by stearoyl-CoA desaturase-1 activity. SCD1 is a key enzyme involved in oleic acid-induced migration of HTR8/SVneo cells. Regulatory effects of oleic acid and SCD1 on oxidative stress in HTR8/SVneo cells, effects of oleic acid and elaidic acid on proliferation and migration of HTR8/SVneo cell lines, overview | Homo sapiens |