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Literature summary for 1.14.19.1 extracted from

  • Jung, W.; Kim, E.J.; Han, S.J.; Choi, H.G.; Kim, S.
    Characterization of stearoyl-CoA desaturases from a psychrophilic antarctic copepod, Tigriopus kingsejongensis (2016), Mar. Biotechnol., 18, 564-574 .
    View publication on PubMed
Search for more literature for 1.14.19.1

Cloned(Commentary)

Cloned (Comment) Organism
gene SCD-1, DNA and amino acid sequence determination and analysis, sequence comparisons, phylogenetic analysis, recombinant expression in Escherichia coli srain BL21(DE3) Tigriopus kingsejongensis
gene SCD-2, DNA and amino acid sequence determination and analysis, sequence comparisons, phylogenetic analysis, recombinant expression in Escherichia coli srain BL21(DE3) Tigriopus kingsejongensis

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane transmembrane enzyme Tigriopus kingsejongensis 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
palmitoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+ Tigriopus kingsejongensis
-
 palmitoleoyl-CoA + 2 ferricytochrome b5 + 2 H2O
-
 ?
stearoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+ Tigriopus kingsejongensis
-
 oleoyl-CoA + 2 ferricytochrome b5 + 2 H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Tigriopus kingsejongensis
-
 collected in a tidal pool near the King Sejong Station, King George Island, Antarctica
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
palmitoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+
-
 Tigriopus kingsejongensis palmitoleoyl-CoA + 2 ferricytochrome b5 + 2 H2O
-
 ?
stearoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+
-
 Tigriopus kingsejongensis oleoyl-CoA + 2 ferricytochrome b5 + 2 H2O
-
 ?

Subunits

Subunits Comment Organism
? x * 26100, about, sequence calculation Tigriopus kingsejongensis
? x * 43100, about, sequence calculation Tigriopus kingsejongensis

Synonyms

Synonyms Comment Organism
SCD-1
-
 Tigriopus kingsejongensis
SCD-2
-
 Tigriopus kingsejongensis
stearoyl-CoA desaturase
-
 Tigriopus kingsejongensis
TkSCD-1
-
 Tigriopus kingsejongensis
TkSCD-2
-
 Tigriopus kingsejongensis

Cofactor

Cofactor Comment Organism Structure
cytochrome b5
-
 Tigriopus kingsejongensis

General Information

General Information Comment Organism
additional information a second transmembrane domain integrated in the membrane seems to be critical for desaturase activity Tigriopus kingsejongensis
physiological function both SCD genes from an Antarctic marine copepod encode a functional desaturase that is capable of increasing the amounts of palmitoleic acid and oleic acid in a prokaryotic expression system Tigriopus kingsejongensis