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Literature summary for 1.14.19.1 extracted from

  • Alloatti, A.; Gupta, S.; Gualdron-Lopez, M.; Nguewa, P.A.; Altabe, S.G.; Deumer, G.; Wallemacq, P.; Michels, P.A.; Uttaro, A.D.
    Stearoyl-CoA desaturase is an essential enzyme for the parasitic protist Trypanosoma brucei (2011), Biochem. Biophys. Res. Commun., 412, 286-290.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
isoxyl
-
Trypanosoma brucei

Organism

Organism UniProt Comment Textmining
Trypanosoma brucei
-
-
-
Trypanosoma brucei Lister 427
-
-
-

Synonyms

Synonyms Comment Organism
SCD
-
Trypanosoma brucei
stearoyl-CoA desaturase
-
Trypanosoma brucei

General Information

General Information Comment Organism
malfunction enzyme inhibition by genetic and chemical tools is detrimental for parasite development. The partial ablation of the enzyme inhibits drastically the parasite growth Trypanosoma brucei